An Oklahoma judge on Monday ordered Johnson & Johnson (J&J) to pay $572.1 million to the state for their role in the state’s opioid crisis. The first trial of an opioid manufacturer, the decision is also the first holding a drug-maker culpable for the opioid epidemic.

Oklahoma Attorney General Mike Hunter alleged that J&J’s false and misleading marketing practices substantially contributed to Oklahoma’s opioid epidemic through major oversupply of the painkillers. In the suit, the state sought $17 billion to abate the crisis, allegedly caused by J&J.

Over the course of a seven-week, non-jury trial, J&J argued their marketing of two products, which they claim were not misleading or false, could not have single-handily caused the entire Oklahoma opioid crisis. Additionally, J&J contested their liability due to ownership of Tasmanian Alkaloids, the dominant supplier of opium.

Nevertheless, Judge Thad Balkman ruled against J&J, finding that the state proved that the company’s false and misleading promotion of its opioid products created a public nuisance in the form of an opioid epidemic. As such, the state was entitled to $572.1 million to abate the nuisance appropriately.

The judgment is expected to have far-reaching implications, setting precedent for more than 2,000 pending opioid lawsuits. In a statement, J&J said the company plans to appeal the ruling.